Collapsible airways contributing to airflow limitation.
نویسنده
چکیده
منابع مشابه
Pathophysiology of the small airways in chronic obstructive pulmonary disease.
Chronic obstructive pulmonary disease (COPD) is characterized by a persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. From a pathological point of view, COPD is characterized by two distinct and frequently coexisting aspects: small airway abnormalities and parenchymal ...
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Patients with chronic obstructive pulmonary disease (COPD) exhibit increases in lung volume due to expiratory airflow limitation. Increases in lung volumes may affect upper airway patency and compensatory responses to inspiratory flow limitation (IFL) during sleep. We hypothesized that COPD patients have less collapsible airways inversely proportional to their lung volumes, and that the presenc...
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The pathological hallmarks of chronic obstructive pulmonary disease (COPD) are inflammation of the small airways (bronchiolitis) and destruction of lung parenchyma (emphysema). The functional consequence of these abnormalities is airflow limitation. Airway abnormalities and emphysema interact in a complex fashion in the development of airflow limitation in COPD. In an attempt to improve underst...
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BACKGROUND Computed tomography (CT) has been used for non-invasive quantitative assessment of airway dimensions, potentially showing airway remodeling, in asthma. However, most studies have examined either only one airway or only airways in anatomically unidentified cross-sections. Using software capable of precisely identifying the generation of airways and measuring airway dimensions perpendi...
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This review focuses on the major cellular and structural changes present in the airways and lung parenchyma in asthma in comparison with chronic obstructive pulmonary disease (COPD) in an attempt to underline the possible mechanisms contributing to airflow limitation in these two diseases. Both asthma and COPD are characterized by a thickening of the airway wall and by the presence of an inflam...
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ورودعنوان ژورنال:
- Chest
دوره 108 4 شماره
صفحات -
تاریخ انتشار 1995